Answers for a gluten-sensitive gut
Coeliac Screen
Coeliac disease is an immune reaction to gluten, and its signs are easy to mistake for everyday digestive upset: bloating, stomach pain, loose stools, fatigue and a general sense of being run down. This screen measures tissue transglutaminase IgA (tTG), the antibody most closely associated with the condition, alongside total IgA to confirm your result can be read accurately.
Your sample is a simple venous draw, taken in our private Leigh-on-Sea clinic and analysed by an accredited UK laboratory. Every result is reviewed and explained in a doctor’s report, giving you a clearer picture of whether gluten is behind your symptoms and a sound basis for the conversation to have next with your GP.
One thing matters before you book: keep eating gluten as you normally would in the weeks leading up to your test. The screen looks for your body’s immune response to it, so removing gluten from your diet beforehand can mask the very antibodies we are measuring and return a falsely reassuring result.
Preparation: No fasting required. Crucially, keep eating gluten as normal, at least one gluten-containing meal a day in the weeks before your test, so the antibodies can be measured accurately. Do not cut gluten out beforehand.
Inside this panel
2 biomarkers
- Coeliac antibodies2 markers
- Tissue Transglutaminase IgA (tTG-IgA)
- Total Immunoglobulin A (IgA)
Worth considering if
- Bloating after eating
- Stomach pain or cramps
- Loose or frequent stools
- Persistent fatigue
- Unexplained weight loss
- Brain fog or low mood
Who this test suits
- Anyone with ongoing digestive symptoms linked to eating
- People with a family history of coeliac disease
- Those with unexplained fatigue or iron deficiency
- Anyone considering a gluten-free diet who wants to test first
- 1
Book your time
Choose a slot that suits you. Appointments only, so the clinic is yours.
- 2
A gentle draw
Demi takes your venous sample in minutes, in a calm private room.
- 3
Doctor-reviewed report
Your results arrive within 5–7 working days, explained marker by marker.
About this test
Tissue transglutaminase IgA is the antibody most linked to coeliac disease, while total IgA confirms your result can be interpreted correctly. Together they give a clear first indication of whether gluten is the problem.
The test detects your immune response to gluten. If you have already removed it from your diet, antibody levels can fall and mask the condition, so it is worth staying on your normal diet until after your draw.
Most reports are returned within 5–7 working days of your sample reaching the laboratory, reviewed and explained by a doctor.


